Lily Gladstone (born August 2, 1986) is an American actress of Blackfeet and Nimíipuu heritage. She made her film debut in Jimmy P: Psychotherapy of a Plains Indian (2012), and went on to collaborate with filmmaker Kelly Reichardt in the independent films Certain Women (2016) and First Cow (2019). Her portrayal of a rancher in the former earned her a nomination for the Independent Spirit Award for Best Supporting Female.

Gladstone appeared in episodes of HBO’s Room 104 (2017–2020), Showtime’s Billions (2019–2023), and FX’s Reservation Dogs (2021–2023). In 2023, she played a lead role in Martin Scorsese’s drama film Killers of the Flower Moon.